2.1.2 From Dusk Till Dawn 3: The Hangman's Daughter.
In the 2014 TV series, she was portrayed by Eiza González. In the third film, she was portrayed by Ara Celi. In the first film, she was portrayed by Salma Hayek, who later played Elena Sanchez in Savages and Claire Luna in Like a Boss.
Initially presented to her captive, entranced audience as an illustrious and highly arousing exotic dancer, Santanico reveals herself and the Titty Twister's glamorous clientele to be a horde of ravenous, monstrous and aggressive vampires with her.
She is the queen of the vampires that hides in the Titty Twister. She stars as the main attraction at the Titty Twister, a seedy and smutty hole-in-the-wall bar and strip joint just over the border of Mexico where criminal brothers Seth Gecko and Richie Gecko flee to with a family of hostages in tow. Santánico Pandemónium (also spelled Santanico Pandemonium) is the main antagonist of the 1996 horror crime action thriller film From Dusk Till Dawn. ~ Santánico Pandemónium in her vampire form.